![]() 1, 2 Since then, elective embryo transfer and “freeze-all” strategy with segmentation of in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) treatment, aiming to cryopreserve all good quality embryos produced in a fresh cycle and to transfer these embryos in subsequent endometrial prepared cycles, has been widely used in assisted reproductive technology (ART) in recent years. The first successful frozen-thawed embryo transfer (FET) was reported in 1983 and the first live birth in 1984. Keywords: polycystic ovarian syndrome, stimulated cycle, hormone replacement cycle, frozen-thawed embryo transfer, endometrial preparation, propensity score matching Eventually, we must embrace the concepts of individualization, securitization, and optimization in the clinic. However, STC may reduce unnecessary anxiety and operational costs and offer more flexibility for patients. Evidence is available which shows that for young women with PCOS in preparation for FET, HRC could be a reasonable choice for patients who are unwilling to accept injections. ![]() Subsequent multivariate logistic regression analysis also yielded similar results.Ĭonclusion: STC for endometrial preparation had similar pregnancy outcomes compared with HRC protocols. After PSM, 199 patients were included in both groups, respectively. Results: Data on 1234 HRC protocols (86% of the total) and 200 STC protocols (14%) were collected. Pregnancy outcomes of couples undergoing routine STC-FET or HRC-FET were analyzed by propensity score matching (PSM) and multivariable logistic regression analyses. Methods: We conducted a retrospective study of 1434 FET cycles from January, 2017 to March, 2020 in our reproductive center, in which stimulated and hormone replacement cycles were used for endometrial preparation. Objective: The principal purpose of this study was to compare reproductive outcomes for stimulated cycles (STC) and hormone replacement cycles (HRC) for endometrial preparation before frozen-thawed embryo transfer (FET) in young women with polycystic ovary syndrome (PCOS). Li Li, 1 Dan-Dan Gao, 2 Yi Zhang, 2 Jing-Yan Song, 1 Zhen-Gao Sun 3ġThe First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, 250014, People’s Republic of China 2The College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, People’s Republic of China 3Reproductive and Genetic Center of Integrated Medicine, The Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250011, People’s Republic of ChinaĬorrespondence: Jing-Yan Song Zhen-Gao Sun Tel +86 18765800113Įmail
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